Application of Nanotechnology in Cancer Therapy and Imaging

By Xu Wang, Lily Yang, Zhuo Georgia Chen, D. Shin. Ca, 2008

661 citations recorded by the source corpus.

Recent developments in nanotechnology have provided researchers with new tools for cancer imaging and treatment. This technology has enabled the development of nanoscale devices that can be conjugated with several functional molecules simultaneously, including tumor‐specific ligands, antibodies, anticancer drugs, and imaging probes. Since these nanodevices are 100 to 1,000‐fold smaller than cancer cells, they can be easily transferred through leaky blood vessels and interact with targeted tumor‐specific proteins both on the surface of and inside cancer cells. Therefore, their application as cancer cell‐specific delivery vehicles will be a significant addition to the currently available armory for cancer therapeutics and imaging.

Subfields: Biomaterials, Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/76fa432d1e28c4548c849770eca7b08b4db8c528

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In Biomaterials

In Biomedical Engineering

Citations in the corpus

Cancer active targeting by nanoparticles: a comprehensive review of literature (2014, methodology): “Furthermore, active targeting of nanocarriers with small molecule therapeutic cargo has shown the potential to suppress multidrug resistance (MDR) via bypassing of P-glycoprotein-mediated drug efflux (Yu et al. 2010; Talekar et al. 2011; Wang et al. 2008).”
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Nanoparticles for Cancer Therapy: Current Progress and Challenges (2021, background): “This product further reacts with acrylic acid to give rise to hexa-acid, which further produces “hexa-amine” (Generation 1) product and so on [61].”
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