Chlorogenic acid and caffeic acid are absorbed in humans.

By M. Olthof, P. Hollman, M. Katan. Journal of NutriLife, 2001

946 citations recorded by the source corpus.

Subfields: Physiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/76c3d47232fab666702795d69250c5f1a8a815cb

How researchers see this paper

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1. Claudine Manach
2. M. D’Archivio
3. Augustin Scalbert
4. K. Pandey
5. R. Masella
6. M. M. Rahman
7. G. Williamson
8. Roberta Di Benedetto

Citations in the corpus

• Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome (2017, background): “The proposed mechanism is supported by the fact that chlorogenic acid can be found intact in the small intestine of humans [58].”
• Breeding for chlorogenic acid content in eggplant: interest and prospects. (2013, background): “, 2001), fruits and vegetables also make a substantial contribution to CGA intake (Olthof et al., 2001).”
• Role of Chlorogenic Acids in Controlling Oxidative and Inflammatory Stress Conditions (2015, neutral): “8 mmol) of CQAs [40].”
• Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. (2005, background): “Intact chlorogenic acid has been detected at low concentrations in nonhydrolyzed urine samples (138, 147).”
• Polyphenols, dietary sources and bioavailability. (2007, background): “However these compounds are naturally esterified in plant products, and this impairs their absorption because intestinal mucosa, liver and plasma do not possess esterases capable of hydrolyzing chlorogenic acid to release caffeic acid [103, 104], and hydrolysis can be performed only by the colonic m”
• Plant polyphenols as dietary antioxidants in human health and disease (2009, background): “However these compounds are naturally esterified in plant products and esterification impairs their absorption because intestinal mucosa, liver and plasma do not possess esterases capable of hydrolyzing chlorogenic acid to release caffeic acid, and hydrolysis can be performed only by the microflora ”
• Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects (2021, background): “These chemicals are naturally esterified in plant products, and esterification hinders their absorption [68].”
• Regulated Water Deficits Improve Phytochemical Concentration in Lettuce (2010, background): “Among the major phenolic compounds in lettuce known to have health-promoting qualities are chlorogenic acid, caffeic acid, and chicoric acid (Graefe and Veit, 1999; Olthof et al., 2001).”