Multiple High-Throughput Analyses Monitor the Response of E. coli to Perturbations
By Nobuyoshi Ishii, K. Nakahigashi, T. Baba, M. Robert, Tomoyoshi Soga, A. Kanai, Takashi Hirasawa, M. Naba, Kenta Hirai, Aminul Hoque and 19 more. Science, 2007
689 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/75ca1976bb8734f5cbc5fd1526d135d069d5f061
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In Molecular Biology
- Cholsoon Jang
- Li Chen
- V. Schachter
- Pierre-Yves Bourguignon
- Maxime Durot
- Daniel Machado
- Markus J. Herrgård
- Joshua D. Rabinowitz
Citations in the corpus
- Systematic Evaluation of Methods for Integration of Transcriptomic Data into Constraint-Based Models of Metabolism (2014, methodology): “From these candidate datasets we selected the three that had intracellular flux profiles and transcriptome data: Ishii et al [40] and Holm et al [41] datasets for E. coli ; and Rintala et al dataset for yeast [42].”
- Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation (2008, background): “This ambitious goal will require the integration of diverse and comprehensive data sets, and the application of interdisciplinary approaches to model regulatory networks that are triggered by environmental factor”
- Genome-scale models of bacterial metabolism: reconstruction and applications (2008, background): “These data-sets provide partial yet comprehensive snapshots of cellular mechanisms (Ishii et al ., 2007a), but their interpretation is made difficult by the volume of data.”
- Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy (2008, methodology): “As in microbial flux determination, computational data integration is achieved by a genetic algorithm that searches for flux combinations consistent with the experimental dat”
- Metabolomics and isotope tracing (2018, background): “coli and yeast, single knockout of an enzyme has only a modest effect on the overall metabolome, mainly accumulation of metabolites directly upstream of the eliminated enzyme (Ishii et al., 2007; Ewald et al., 2013).”