The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.

By Morgan Tucker, M. A. Valencia-Sanchez, R. R. Staples, Junji Chen, C. Denis, R. Parker. Cell, 2001

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The Arabidopsis Cold-Responsive Transcriptome and Its Regulation by ICE1w⃞ (2005, background): “CAF1 is a critical component of the major cytoplasmic deadenylase in yeast, which initiates mRNA turnover by shortening of the poly(A) tail (Tucker et al., 2001).”
P-bodies and stress granules: possible roles in the control of translation and mRNA degradation. (2012, background): “2007) by the major mRNA deadenylase, the Ccr4/Pop2/Not complex (Daugeron et al. 2001; Tucker et al. 2001; Thore et al. 2003).”
The cap-to-tail guide to mRNA turnover (2001, background): “, but might also participate in cytoplasmic deadenylatio”