Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of…

By N. Vionnet, E. Hani, S. Dupont, S. Gallina, S. Francke, Sébastien Dotte, Frédérique De Matos, E. Durand, F. Leprêtre, C. Lecoeur and 4 more. American Journal of Human Genetics, 2000

715 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics

View Paper: https://www.semanticscholar.org/paper/7205e3f01a36a9b8c1b55f02abe5ef1401609a37

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Citations in the corpus

• Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. (2002, background): “Our present findings are consistent with recent reports of susceptibility loci for type 2 diabetes (11) and the quantitative trait loci for insulin resistance (12) being mapped to chromosome 3q27, where the adiponectin gene is located.”
• Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. (2001, background): “Furthermore, a diabetes susceptibility locus has been mapped to chromosome 3q27, the location of the human Acrp30 gene (18).”
• Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 (2022, background): “The human fetuin-A or the AHSG gene is located on chromosome 3q27, which has been identified as T2DM susceptibility locus [95] and has been mapped as a quantitative trait locus for MetS [96].”