Zinc and its role in immunity and inflammation.

By Paola Bonaventura, Giulia Benedetti, F. Albarède, P. Miossec. Autoimmunity Reviews, 2015

729 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection (2020, background): “Zinc • Impaired DTH skin responses [8,131,132] • Impaired survival, proliferation and maturation of monocytes, NK cells, T and B cells [133] • Impaired NK cell activity [8] • Impaired phagocytosis by macrophages and neutrophils [8] • Altered cytokine production, contributing to greater oxidative str”
Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling (2017, background): “Zinc is also crucial for the balance between the different T-cell subsets (Foster and Samman 2012; Haase and Rink 2014; Bonaventura et al. 2015).”
Zinc and Oxidative Stress: Current Mechanisms (2017, background): “MTF-1 activates the expression of the Selenoprotein 1 (Sepw1) gene, which encodes an antioxidant glutathione-binding protein which scavenges free radicals [26].”