Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

By N. Perkins. Oncogene, 2006

703 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6f972a5be3330bae0b8e8525f69810567f817307

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. S. Ghosh
2. M. Hayden
3. A. West
4. Gregory E. Miller
5. E. Seto
6. Steve W. Cole
7. T. Gilmore
8. E. Chen

In Immunology

1. S. Ghosh
2. M. Hayden
3. A. West
4. Gregory E. Miller
5. Angelika Schmidt
6. E. Seto
7. P. Krammer
8. Steve W. Cole

In Molecular Biology

1. M. Hayden
2. Xiang-Jiao Yang
3. S. Ghosh
4. E. Seto
5. Gregory E. Miller
6. P. Krammer
7. Michael S. Kobor
8. T. Gilmore

Citations in the corpus

• NF-κB and the immune response (2006, background): “Progress continues to be made in understanding AgR signaling to NF-kB, and this work has led to the appreciation of regulatory ubiquitination events in IKK activation (see reviews by Perkins, 2006; Scheidereit, 2006).”
• Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling (2009, background): “And the activity of NF- B itself can be markedly altered by posttranslational modifications, such as acetylation, ubiquitination, and phosphorylation (25).”
• Introduction to NF-κB: players, pathways, perspectives (2006, background): “…the dynamics and direct mechanisms of gene regulation by NF-kB (Hoffmann et al., 2006); post-translational modifications that regulate components of the NF-kB pathway (Perkins, 2006); and the controversial role of reactive oxygen species in the regulation of NF-kB activity (Bubici et al., 2006).”
• Molecular Mechanisms of Treg-Mediated T Cell Suppression (2012, background): “The NF-κB complex itself can be phosphorylated and acetylated , which regulates its transcriptional activity and association with other transcription factors (Li and Verma, 2002; Perkins, 2006).”
• Lysine acetylation: codified crosstalk with other posttranslational modifications (2008, background): “It remains to be established whether similar interplay occurs in p53, FoxO1, RelA (NF-kB subunit) (Perkins, 2006), and CCAAT/enhancer binding protein b (C/EBPb) (Hasselgren, 2007).”