Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.

By J. Cavaillé, K. Buiting, M. Kiefmann, M. Lalande, C. Brannan, B. Horsthemke, J. Bachellerie, Jürgen Brosius, A. Hüttenhofer. Proceedings of the National Academy of Sciences of the United States of America, 2000

605 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6f7e9154e2bd6c9ca00d3b7d6249d99f5e21d837

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. John S. Mattick
2. Sean R. Eddy
3. Igor V. Makunin
4. Kimberly R. Kukurba
5. Stephen B. Montgomery
6. Marcel E. Dinger
7. Howard Y. Chang

In Genetics

1. Sean R. Eddy
2. John S. Mattick
3. Igor V. Makunin
4. T. Cooper
5. Gregory M. Cooper
6. Jay Shendure
7. Gernot G. Presting

In Molecular Biology

1. John S. Mattick
2. Igor V. Makunin
3. Guey-Shin Wang
4. Sean R. Eddy
5. T. Cooper
6. Travis J. Wheeler
7. Eric P. Nawrocki
8. Peer Bork

Citations in the corpus

• Splicing in disease: disruption of the splicing code and the decoding machinery (2007, background): “SnoRNAs typically serve as guide RNAs that target modifications of ribosomal RNA (rRNAs), tRNAs or snRNAs; however, HBII-52 snoRNA was found to have a conserved 18-bp region that is complementary to the serotonin receptor 2C (5-HC 2C R) gene near an alternative 5′ splice sit”
• Introns in gene evolution. (2003, background): “In 2000, Cavaille et al. (2000) found snoRNA-like molecules specifically expressed in mammalian brain.”
• Non–coding RNA genes and the modern RNA world (2001, background): “(The imprinted Prader–Willi crucial region seems to be especially rich in ncRNA”
• Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. (2002, neutral): “This may indicate thatgene also encodes a brain-specific box H/ACA snoRNA the substrate repertoire of 2 -O-methylation and pseu-of unknown function (Cavaillé et al., 2000). douridylation guide snoRNAs is much broader than hasEvolutionary Origin of the snoRNA-Mediated been demonstrated to date.”
• Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs (2007, background): “and perhaps at least one brain-specific mRNA in mammal”
• Non-coding RNA. (2006, background): “There are also a number of so-called orphan snoRNAs without known targets (101,102,123,128,130,131).”