Towards safe, non-viral therapeutic gene expression in humans

By Dominic J. Glover, H. Lipps, D. Jans. Nature reviews genetics, 2005

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How researchers see this paper

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Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics (2009, positive): “Substantial progress has been made in the design of new technologies to improve cellular uptake of therapeutic compounds (Opalinska and Gewirtz, 2002; Järver and Langel, 2004; Glover et al., 2005; Torchilin, 2005; De Fougerolles et al., 2007; Kong and Mooney, 2007).”
Non viral vectors in gene therapy- an overview. (2015, background): “However the application of non-viral gene transfer have been ignored for a long time in past because of their poor efficiency of delivery thereby low transient expression of their transgenes [2].”
Mammalian cell transfection: the present and the future (2010, neutral): “1a) [2].”