miRBase: the microRNA sequence database.

By Sam Griffiths-Jones. Methods in molecular biology, 2006

702 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6ecb2f55ae787363712adf6e7ba6c2812d3f0b32

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Citations in the corpus

The Diploid Genome Sequence of an Individual Human (2007, background): “These genomic datasets have also enabled the identification of additional functional sequence such as cis-regulatory DNA [24–29] as well as both noncoding and microRNA [30–34] .”
miRWalk - Database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes (2011, background): “The miRNA gene family is one of the largest in higher eukaryotes: more than 700 miRNAs have been identified in the human genome [9], each of them having the potential to bind to hundreds of transcripts.”
MicroRNA: Biogenesis, Function and Role in Cancer (2010, background): “Extensive research over the last decade revealed that miRNA are more prevalent that originally thought, with 940 miRNA identified to date in humans and over 1000 predicted [9-11, 330].”
miR-19 is a key oncogenic component of mir-17-92. (2009, background): “miR-19 is evolutionarily conserved across many vertebrate species (Griffiths-Jones 2006).”
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (2008, background): “The current commercially available high-throughput methodologies rely on primers or probes designed to detect each of the current reference miRNA sequences residing in miRBase, which acts as the central repository for known miRNAs (Griffiths-Jones 2006).”
The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (2008, methodology): “…numerous recent studies have shown that changes in miRNA levels lead to altered levels of mRNA targets (Lim et al., 2005; Wang and Wang, 2006; Grimson et al., 2007), we performed correlative mRNA studies on a subset of the cases of nondemented (n 4), MCI (n 4), and AD (n 3) brains using the…”
MicroRNA-directed transcriptional gene silencing in mammalian cells (2008, background): “We proceeded to test this hypothesis by analyzing miR-320, whose mature sequence has been cloned and is conserved in human, mouse, rat, and cow (13).”
A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence (2008, methodology): “For both datasets, discovered motifs were matched against known human miRNAs obtained from miRBase (18, 19).”