Liver regeneration: from myth to mechanism

By R. Taub. Nature reviews. Molecular cell biology, 2004

1,584 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Surgery

View Paper: https://www.semanticscholar.org/paper/6e1b50b56df646fa459e8c0ba625fc9bec64fbcb

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Citations in the corpus

Chapter 1. General introduction (2015, neutral): “After liver surgery with a reduction of the hepatic cell mass, a ‘survival programme’ may start for vital liver functions [12].”
Kupffer Cells in the Liver (2013, positive): “The association between enhanced expression of inﬂamma-tory cytokines and the initiation of cell cycle progression by hepatocytes has been well described in response to partial hepatectomy, where the rapid and transient expression of cytokines programs hepatocytes for rapid proliferation (137).”
Epithelial stem cells: turning over new leaves. (2007, positive): “Rather, liver regeneration after a partial hepatectomy occurs through proliferation of hepatocytes (Taub, 2004).”
Immunobiology and pathogenesis of viral hepatitis. (2006, background): “Studies by Taub (192), Fausto (190, 191), and others (197) have defined the role of many immediate-early gene products in the initial phase of hepatocyte regeneration after partial hepatectomy.”
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. (2012, background): “Considering that epithelial tissues of the forestomach and intestine are composed of proliferating cells and that approximately 80% of the liver is composed of normally quiescent hepatocytes (Taub, 2004), we assumed that Nrf2 could effectively activate metabolic genes in the presence of proliferativ”
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. (2006, positive): “For example, in the adult mammalian liver, partial hepatectomy stimulates proliferation in approximately 95% of remaining hepatocytes ( Taub, 2004 ).”
Hepatic stellate cells in liver development, regeneration, and cancer. (2013, background): “when it attains the mass required for the needs of the organism (88).”
Liver regeneration after partial hepatectomy: critical analysis of mechanistic dilemmas. (2010, background): “Such information has also been provided in other reviews on the subject.(1,31,32) The purpose of this review is to concentrate on aspects of liver regeneration least understood and to provide recent and classic information that helps formulate the mechanistic dilemmas of the field.”
Programmed Cell Death in Animal Development and Disease (2011, neutral): “Inmammals, the regenerative capacity of the liver enables restoration of full organ mass within a very short time frame, even after 70% of the liver has been removed (Taub, 2004).”
Liver regeneration (2007, background): “PHx induces rapid induction of more than 100 genes not expressed in normal liver (Taub, 1996, 2004).”
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, neutral): “…connective tissue, endothelial cells of the sinusoids, Kupffer cells functioning as in situ macrophages and immune cells, such as lymphocytes (T cells, B cells, natural killer (NK) and especially NKt cells) and leukocytes (neutrophils, monocytes and dendritic cells) (Taub 2004; Tacke et al. 2009).”