IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro

By Sean Bendall, Morag H. Stewart, P. Menéndez, D. George, Kausalia Vijayaragavan, T. Werbowetski-Ogilvie, Verónica Ramos-Mejía, A. Rouleau, Jiabi Yang, M. Bosse and 2 more. Nature, 2007

636 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6dd97ebc314054b0e5a102272a4a0d8ffc6fbfdd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. José C. R. Silva
2. Donald E. Ingber
3. X. Chen
4. Carmel Majidi

In Molecular Biology

1. José C. R. Silva
2. Jesús Gil
3. J. Lieberman
4. Donald E. Ingber
5. E. Song
6. X. Chen
7. L. Vallier
8. A. Pocheville

Citations in the corpus

• The cerebrospinal fluid provides a proliferative niche for neural progenitor cells (2011, background): “…in the CSF and their action on progenitors across the apical surface may be a model for other epithelia including lung, gut, and vascular endothelia 902 Neuron 69, 893–905, March 10, 2011 ª2011 Elsevier Inc. that develop in relation to extracellular fluids (Bendall et al., 2007; Scadden, 2006).”
• let-7 regulates self renewal and tumorigenicity of breast cancer cells. (2007, background): “It may be that the multipotency of the T-IC provides a means to generate not only the tumor but the supporting niche cells necessary to sustain it, as has recently been shown for human ES cells (Bendall et al., 2007).”
• Senescence impairs successful reprogramming to pluripotent stem cells. (2009, positive): “(Bendall et al., 2007). hES cells can also be propagated in feederfree conditions, conditioned media or serum replacement if a combination of Activin plus FGF2 is used (Beattie et al., 2005; Vallier et al., 2005).”
• Mechanical control of tissue and organ development (2010, background): “However, these mechanical cues must be integrated with other chemical signals, such as growth factors (e.g. insulin-like growth factor or fibroblast growth factor) (Bendall et al., 2007), to exert effective developmental control.”
• The Ecological Niche: History and Recent Controversies (2015, background): “Conversely, stem cells can induce the formation of niches (Bendall et al. 2007 ).”