An Oxidative Enzyme Boosting the Enzymatic Conversion of Recalcitrant Polysaccharides

By G. Vaaje-Kolstad, B. Westereng, S. Horn, Zhanliang Liu, H. Zhai, M. Sørlie, V. Eijsink. Science, 2010

1,239 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Biotechnology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6b613fff5be0481603851fb95e73bffcc5676190

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In Biomedical Engineering

1. Bernard Henrissat
2. C. Ivanova
3. Feng Xu
4. B. Seiboth
5. T. Lundell
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In Biotechnology

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4. C. Ivanova
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In Molecular Biology

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Citations in the corpus

• Fungal enzyme sets for plant polysaccharide degradation (2011, background): “Although they are involved in improving the efficiency of degrading tightly packed cellulose microfibrils, the precise function of GH61 enzymes is still unknown (Harris et al. 2010; Vaaje-Kolstad et al. 2010).”
• Trichoderma reesei: A Fungal Enzyme Producer for Cellulosic Biofuels (2011, background): “CBP21 has a new enzymatic mechanism that introduces chain breaks by generating oxidized ends and thus opening up the rigid structure of crystalline chitin and making it accessible polysaccharide material for hydrolysis by normal glycoside hydrolases (Vaaje-Kolstad et al., 2010).”
• Lignocellulosic biomass: Biosynthesis, degradation, and industrial utilization (2016, background): “Recently a protein, CBP21 (from chitin-binding protein), acting on crystalline chitin was found to increase the catalytic conversion of the substrate by introducing chain breaks and creating a chain end with a C1oxidized sugar [30].”
• Enzymatic breakdown of lignocellulosic biomass: the role of glycosyl hydrolases and lytic polysaccharide monooxygenases (2017, methodology): “that copper is the native metal co-factor of LPMOs [102].”
• Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components (2011, background): “The GH61 product profile can be contrasted with that resulting from the action of the structurally related CBP21 enzyme on chitin, where only even-numbered DP oligosaccharides with aldonic acid termini are produced (17).”
• Novel enzymes for the degradation of cellulose (2012, background): “Inspired by the findings for CBP21 [8] and earlier indications that certain CBM33s may act synergistically with cellulases [53] studies were initiated to see if certain CBM33s act on cellulose like CBP21 acts on chitin.”
• The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes (2012, result): “Formerly recognized as a family with weak endoglucanase activity (62, 63), recent data support the view that GH61 comprises proteins that lack hydrolytic and endoglucanase activity (64, 65), but that may perform an oxidative attack of crystalline cellulose (66).”
• Lignocellulases: a review of emerging and developing enzymes, systems, and practices (2017, background): “According to reports, LPMOs complement the functionality of the canonical cellulases by improving substrate accessibility and introducing chain breaks in the cellulose strand by oxidative means (Vaaje-Kolstad et al. 2010; Horn et al. 2012).”
• Visions of Sustainability in Bioeconomy Research (2014, neutral): “…al. [67] New Biotechnology Resources II Navia et al. [68] Waste [91] Journal of Cleaner Production Processing and Technology I Vaaje-Kolstad et al. [92] Science Processing and Technology II Van Dam et al. [93] Industrial Crops and Products Resources II Vaneeckhaute et al. [94] Water, Air, & Soil…”