The p300/CBP acetyltransferases function as transcriptional coactivators of β‐catenin in vertebrates

By A. Hecht, K. Vleminckx, Marc P. Stemmler, F. van Roy, R. Kemler. EMBO Journal, 2000

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β-Catenin hits chromatin: regulation of Wnt target gene activation (2009, background): “The prominent HAT proteins CBP (also known as CREBBP) and p300 interact with the β-catenin region R10–C (Ref”
Wnt signaling in the intestinal epithelium: from endoderm to cancer. (2005, background): “Two of these factors include the histone acetylase CBP/p300 and the SWI/SNF component BRG1 (Hecht et al. 2000; Takemaru and Moon 2000; Barker et al. 2001).”
The Wnt signaling pathway in development and disease. (2004, background): “CBP may bind to the β-catenin/TCF complex as a coactivator (Hecht et al. 2000, Takemaru & Moon 2000), a hypothesis that remains to be tested directly.”
Maternal β-catenin and E-cadherin in mouse development (2004, background): “…β-catenin to activate transcription either by recruiting general transcription factors to target gene promoters, or by changing chromatin structure (Hecht et al., 2000; Miyagishi et al., 2000; Takemaru and Moon, 2000). βcatenin can also recruit the chromatin-remodeling factor BRG1 to…”
Linking colorectal cancer to Wnt signaling. (2000, background): “…cells that contain high levels of activatedprocess may be achieved by anchorage of the Axin complex at the membrane, in the vicinity of the Frizzled b-catenin, CBP behaves as a transcriptional coactivator of TCF and b-catenin (Hecht et al., 2000; Takemaru andreceptor (Yu et al., 1999) (Figure 1).”