Inactivity produces increases in neurotransmitter release and synapse size.

By Venkatesh N. Murthy, T. Schikorski, C. Stevens, Yongling Zhu. Neuron, 2001

681 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6a10016f688e95edaf1dcc6fd36d21f322381317

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Gina G. Turrigiano
2. Niraj S. Desai
3. A. Watt
4. Wulfram Gerstner
5. G. Davis
6. Richard L. Huganir
7. J. Shepherd
8. Kristen M. Harris

In Molecular Biology

1. Gina G. Turrigiano
2. G. Davis
3. J. Shepherd
4. Richard L. Huganir
5. Kristen M. Harris
6. Niraj S. Desai
7. Terrence J. Sejnowski
8. Jennifer N. Bourne

Citations in the corpus

• Dendritic excitability and synaptic plasticity. (2008, neutral): “In some cases, both the preand the postsynaptic sides are modified simultaneously (542, 772, 773, 831).”
• Homeostatic plasticity in the developing nervous system (2004, background): “, but there is an increase in synapse size and in the number of docked vesicle”
• Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. (2006, background): “Presynaptic changes such as enlargement of presynaptic terminals and their vesicle pools have also been observed in hippocampal neurons ( Murthy et al., 2001 ).”
• The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses (2008, neutral): “…is highly regulated, and many forms of synaptic plasticity, including some forms of LTP and LTD, are induced through changes in one or more of these trafficking and tethering steps that results in changes in receptor number at the synapse (Malinow and Malenka, 2002; Newpher and Ehlers, 2008).”
• Rapid synaptic scaling induced by changes in postsynaptic firing. (2008, background): “…individual neurons or muscle fibers through expression of an inwardly rectifying K channel can induce a presynaptic form of homeostatic plasticity (Murthy et al., 2001; Paradis et al., 2001), but because this manipulation hyperpolarizes both somatic and dendritic regions of the neuron, it cannot…”
• Cell type-specific structural plasticity of axonal branches and boutons in the adult neocortex. (2006, neutral): “Changes in bouton sizes could reflect changes in synaptic weight ( Murthy et al., 2001; Schikorski and Stevens, 1997).”
• Nanoconnectomic upper bound on the variability of synaptic plasticity (2015, background): “…highly correlated with each other and with physiological measurements of the release probability and the efficacy of the synapse (Harris and Stevens, 1989; Lisman and Harris, 1994; Harris and Sultan, 1995; Schikorski and Stevens, 1997; Murthy et al., 2001; Branco et al., 2008; Bourne et al., 2013).”
• Frontiers in Synaptic Neuroscience Synaptic Neuroscience (positive): “In addition to postsynaptic changes, homeostatic presynaptic changes have also been observed (Murthy et al., 2001; Burrone et al., 2002; De Gois et al., 2005; Erickson et al., 2006; Wierenga et al., 2006; Branco et al., 2008).”
• Homeostatic control of neural activity: from phenomenology to molecular design. (2006, background): “In addition, investigators have also observed changes to active zone architecture and vesicle pool size (Murthy et al. 2001, Thiagarajan et al. 2005).”