Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

By J. Amat, Michael V. Baratta, E. Paul, S. T. Bland, Linda R. Watkins, S. Maier. Nature Neuroscience, 2005

921 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/69f12a32b02490cfb97389e30429f62222351448

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Citations in the corpus

Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. (2007, background): “Animals who have been exposed to inescapable stress display subsequent potentiation of fear and anxiety in unrelated tasks (114–116), whereas control over the stressor promotes resilience (114–116), an effect that depends on the ventromedial prefrontal cortex (114).”
Psychosomatics and psychopathology: looking up and down from the brain. (2005, background): “Importantly, like the heart, sympathoexcitatory subcortical threat circuits are under tonic inhibitory control by the prefrontal cortex (Amat et al., 2005; Thayer, in press).”
Stress and the brain: from adaptation to disease (2005, background): “A recent study indicated that stressor controllability inhibits the stress-induced activation of dorsal raphe serotonergic neurons through infralimbic and prelimbic ventral-medial prefrontal cortex inpu”
Learned Helplessness at Fifty: Insights from Neuroscience (2016, background): “To answer this question Amat et al. (2005) inactivated the ventromedial prefrontal cortex-to-dorsal raphe nucleus pathway during the experience of escapable shock, inescapable shock, or no shock.”
The neurobiology of psychedelic drugs: implications for the treatment of mood disorders (2010, background): “Indeed, recent studies showed that prefrontal 5-HT 2A receptors located on descending projections that control serotonergic activity in the dorsal raphe are involved in stress response”
The ecology of human fear: survival optimization and the nervous system (2015, background): “However, as the artificial predator moves closer, a switch to enhanced activation in the midbrain PAG is observed (Mobbs et al., 2009) This finding was later replicated and extended by showing that panic-related motor errors (wrong button presses resulting in collisions with the virtual walls of the”
The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007, background): “[388]), as well as in interacting with the temporal lobe to faciltate memory formation and retrieval (Buckner and Wheeler [389]).”