A modular design for the clathrin- and actin-mediated endocytosis machinery.

761 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The ESCRT pathway. (2011, background): “…of the heterodimeric Bin/Amphiphysin/Rvs (BAR) domain-containing complex Rvs161/Rvs167 promotes scission by generating Developmental Cell 21, July 19, 2011 ª2011 Elsevier Inc. 83 a highly curved vesicle neck that is stressed by the pulling forces of actin polymerization (Kaksonen et al., 2005).”
The ARP2/3 complex: an actin nucleator comes of age (2006, background): “cerevisiae , the ARP2/3 complex and NPFs including Pan1, myosin-5, Las17 (the WASP homologue) and Abp1 are recruited to endocytic sites prior to, or concomitant with, actin polymerizatio”
Molecular mechanism and physiological functions of clathrin-mediated endocytosis (2011, background): “Pathway modularity At the heart of clathrin-coated vesicle formation is a flexible network of interactions, which can be thought of as being made up of different module”
The WASP–WAVE protein network: connecting the membrane to the cytoskeleton (2007, background): “The discovery of the syndapin (also known as pacsin) family of proteins in mammals showed that N-WASP is involved in vesicular trafficking, particularly in endocytosi”