TRPM8 is required for cold sensation in mice.
By A. Dhaka, Amber N. Murray, Jayanti Mathur, Taryn J. Earley, Matt J. Petrus, Ardem Patapoutian. Neuron, 2007
875 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Complementary and alternative medicine, Sensory Systems
View Paper: https://www.semanticscholar.org/paper/68c56e1f309cb99b010c5a3625217868c90dd941
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cellular and Molecular Neuroscience
- D. Bautista
- D. Julius
- A. Basbaum
- Grégory Scherrer
- Arne May
- Clifford J. Woolf
- Ardem Patapoutian
- R. Medzhitov
In Complementary and alternative medicine
In Sensory Systems
- D. Julius
- D. Bautista
- A. Basbaum
- Grégory Scherrer
- Clifford J. Woolf
- Ardem Patapoutian
- Arne May
- R. Medzhitov
Citations in the corpus
- TRP channels and pain. (2013, background): “Cold stimuli can also be analgesic in the context of inflammation or other injuries, and this phenomenon also appears to be TRPM8 dependent (Dhaka et al. 2007, Proudfoot et al. 2006).”
- TRP Channels (2012, neutral): “In particular, Trpm8 knockout mice had remarkable impairments in thermal responses in the temperature range between 15 and 30◦C and lacked sensitivity to icilin (32,71,85).”
- Cellular and Molecular Mechanisms of Pain (2009, positive): “Likewise, these animals display severe deficits in cold-evoked behavioral responses (Bautista et al., 2007; Colburn et al., 2007; Dhaka et al., 2007) over a wide range of temperatures spanning 30°C to 10°C.”
- Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. (2009, neutral): “Cold plate test was carried out as previously described (Dhaka et al., 2007).”