Molecular regulation of vascular smooth muscle cell differentiation in development and disease.

By G. Owens, Meena S. Kumar, B. Wamhoff. Physiological Reviews, 2004

3,469 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/678c24ebdc7d7bd895b6fc2e995309f4252da931

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Citations in the corpus

Developmental basis of vascular smooth muscle diversity. (2007, neutral): “102 These authors divided the arterial tree into four segments for statistical analysis, (1) coronary arteries, (2) ascending aorta and its major arteries, (3) abdominal aorta at the level of the renal arteries, and (4) terminal abdominal aorta and femoral arteries involved in peripheral vascular di”
Smooth muscle cell phenotypic switching in atherosclerosis. (2012, background): “We have previously identified sufficient regions of the SM a-actin5 and SM MHC8,59 promoters necessary to recapitulate expression patterns of these endogenous genes in transgenic mice and identified numerous cis-regulatory elements required for SMC-specific expression in vivo in transgenic mice.5,60”
Linking actin dynamics and gene transcription to drive cellular motile functions (2010, neutral): “Signals that diminish myocardin and MRTF activity promote excessive proliferation of smooth muscle cells, as occurs during atherosclerosis and restenosi”
Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms (2005, background): “In addition, these growth factors and cytokines induce local residents of the vessel wall such as smooth muscle cells to proliferate, migrate and secrete extracellular matrix (ECM) products, which results in enlargement of the atherom”
Knockout of Adamts7, A Novel CAD Locus in Humans, Reduces Atherosclerosis in Mice (2015, background): “Adamts7 deletion during injury may be confined to the early phase when VSMC migration plays a critical role.(16)”
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. (2008, background): “Many of the smooth muscle genes that are up-regulated in dKO hearts are controlled by SRF (Owens et al. 2004), a predicted target for translational repression by miR-133a (Chen et al. 2006).”
Nanopattern-induced changes in morphology and motility of smooth muscle cells. (2005, result): “The decreased proliferation rate of SMC is similar to that observed in vivo, where SMC proliferate slowly [41].”
The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles. (2012, background): “Owens et al.5 have shown that phenotypic modulation of VSMCs in vivo is mediated, at least in part, by transcription repression.”