Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization
By J. Yamaguchi, K. Kusano, O. Masuo, A. Kawamoto, Marcy Silver, S. Murasawa, M. Bosch-Marce, H. Masuda, Douglas Losordo, J. Isner and 1 more. Circulation, 2003
1,241 citations recorded by the source corpus.
Subfields: Cell Biology, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/66adcf3e2c1ef27396daf79435bf2aab16cf1669
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In Molecular Biology
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In Oncology
Citations in the corpus
- Tumor microenvironment: The role of the tumor stroma in cancer (2007, background): “…marrow-derived EPCs [Takahashi et al., 1999] which are then recruited to tumor sites via ahost of chemokines such as VEGF, angiopoietin, stromal cellderived factor (SDF)-1a [Hattori et al., 2001; Iwaguro et al., 2002; Yamaguchi et al., 2003] secreted by the tumor cells and cells of the stroma.”
- Unchain my heart: the scientific foundations of cardiac repair. (2005, background): “ficking of stem and progenitor cells to ischemic tissue (65), and local delivery of SDF-1 can enhance EPC recruitment and neovascularization (63, 66).”
- The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. (2007, background): “Expression of SDF-1 by perivascular cells serves as a retention signal and is crucial for the maintenance of pro-angiogenic cells within the tissue, as demonstrated by the loss of cells when the SDF-1– CXCR4 axis is blocked and cell accumulation when SDF-1 is upregulated [20,21,30].”
- Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005, background): “Other factors significantly upregulated in the hBMSC-transplanted hearts included IGF-1, well known for its effects on myocardial tissue, including stimulation of cardiac contractility, antiapoptotic effects, and improved remodeling after MI; and stromal cell–derived factor-1α (32), which is a chemo”
- CXCR4–SDF-1 Signalling, Locomotion, Chemotaxis and Adhesion (2003, background): “Furthermore, it had been recently shown that a hypoxic limb upregulates the expression of SDF-1 which chemoattracts CXCR4 positive endothelial progenitor/ stem cells that subsequently may be involved in ischemic neovascularization (Yamaguchi et al. 2003).”
- Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. (2005, background): “Consistently, overexpression of SDF-1 promoted neovascularization of ischemic tissues [18].”