Serotonin receptors.

By David E. Nichols, C. Nichols. Chemical Reviews, 2008

845 citations recorded by the source corpus.

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Physiology of Astroglia. (2018, neutral): “Serotonin (or 5-hydroxytryptamine) is one of the ancient signaling molecules, being produced and released by bacteria, in which it regulates swimming behavior and growth (1215).”
Serotonin, serotonin receptors and their actions in insects (2014, background): “Presently, vertebrate 5-HT receptors are divided into seven main 5-HT receptor families (termed 5-HT1-7) based on their gene organization, sequence similarities, pharmacological properties and downstream signaling pathways ([14,64,65,72-74]).”
QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery (2018, background): “The 5-hydroxytryptamine 1A (5-HT 1A ) serotonin receptor has been an attractive target for treating mood and anxiety disorders such as schizophrenia (Nichols and Nichols, 2008; Lacivita et al., 2012).”
Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action. (2013, background): “Serotonin is a major modulatory neurotransmitter and plays significant roles in behaviors such as eating and sleep, in situations of stress and anxiety, in the development of the human brain, and in the pathophysiology of several diseases (Bloom and Kupfer, 1995; Barnes and Sharp, 1999; Nichols and ”