Serotonin, serotonin receptors and their actions in insects
By Rut Vleugels, H. Verlinden, J. Broeck. 2014
98 citations recorded by the source corpus.
Serotonin is an ancient monoamine neurotransmitter, biochemically derived from tryptophan. It is most abundant in the gastrointestinal tract, but is also present throughout the rest of the body of animals and can even be found in plants and fungi. Serotonin is especially famous for its contributions to feelings of well-being and happiness. More specifically it is involved in learning and memory processes and is hence crucial for certain behaviors throughout the animal kingdom. This brief review will focus on the metabolism, biological role and mode-of-action of serotonin in insects. First, some general aspects of biosynthesis and break-down of serotonin in insects will be discussed, followed by an overview of the functions of serotonin, serotonin receptors and their pharmacology. Throughout this review comparisons are made with the vertebrate serotonergic system. Last but not least, possible applications of pharmacological adjustments of serotonin signaling in insects are discussed.
Subfields: Cellular and Molecular Neuroscience, Insect Science
View Paper: https://www.semanticscholar.org/paper/79469220fb207ca49b60475fc3a90c2286f55fa2
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In Cellular and Molecular Neuroscience
In Insect Science
Citations in the corpus
- From Molecules to Management: Mechanisms and Consequences of Locust Phase Polyphenism (2017, background): “Mianserin was shown to inhibit 5-HT2 and 5-HT7 receptors (Colas et al., 1995; Thamm et al., 2013; Vleugels et al., 2014; for an overview see Vleugels et al., 2015).”