Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action.
By S. Kortagere, A. C. Fontana, Deja R Rose, O. Mortensen. 2013
33 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Spectroscopy, Computational Chemistry & Drug Discovery
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In Molecular Biology
In Computational Chemistry & Drug Discovery
Citations in the corpus
- A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System Targets (2015, background): “Mutagenesis of the allosteric binding site residues predicted to interact with ATM-7 confirmed that SERT affinity for the allosteric ligand was lost (47).”