Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

By J. Boch, H. Scholze, S. Schornack, Angelika Landgraf, S. Hahn, S. Kay, T. Lahaye, A. Nickstadt, U. Bonas. Science, 2009

2,631 citations recorded by the source corpus.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/65dfb6d2fa7bfea36444e347856fb0f36cdcf2b0

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In Plant Science

1. J. Keith Joung
2. Daniel F. Voytas
3. Erin L. Doyle
4. Adam J. Bogdanove
5. Feng Zhang
6. Volker P. Brendel
7. Daniel S. Standage
8. Nicholas J. Booher

Citations in the corpus

• A TALE nuclease architecture for efficient genome editing (2011, background): “Recently, two groups described an approach for engineering DNA-binding specificities based upon TALEs from Xanthomonas plant pathogen”
• RNA-Guided Human Genome Engineering via Cas9 (2013, background): “This RNA-mediated editing process was notably rapid, with the first detectable GFP+ cells appearing ~20 hours post transfection compared with ~40 hours for the AAVS1 TALENs.”
• Signaling in Plant-Microbe Interactions (2013, background): “These T3Es are called TAL (transcription activator like) belonging to conserved AvrBs3/PthA effector family (Boch et al. 2009; Moscou and Bogdanove 2009).”
• Targeting DNA Double-Strand Breaks with TAL Effector Nucleases (2010, background): “Randomly assembled repeat domains have been shown to bind DNA targets predicted by the cipher (Boch et al. 2009); however, custom TALEs designed to recognize new target sequences have not been reported.”
• Genomic Mining of Prokaryotic Repressors for Orthogonal Logic Gates (2013, background): “Several modular scaffolds – zinc finger proteins (ZFPs) 14 and transcription activator-like effectors (TALEs) 15 – have a domain architecture that allows proteins to be designed to bind target sequences.”
• Development and Applications of CRISPR-Cas9 for Genome Engineering (2014, neutral): “…2005; Miller et al., 2007), transcription activator-like effectors (TALEs) from Xanthomonas bacteria (Christian et al., 2010; Miller et al., 2011; Boch et al., 2009; Moscou and Bogdanove, 2009), and most recently the RNA-guided DNA endonuclease Cas9 from the type II bacterial adaptive immune…”
• Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity (2013, background): “…et al., 2007; Porteus and Baltimore, 2003; Sander et al., 2011; Wood et al., 2011) and transcription-activator-like effector nucleases (TALENs) (Boch et al., 2009; Christian et al., 2010; Miller et al., 2011; Moscou and Bogdanove, 2009; Reyon et al., 2012; Sanjana et al., 2012; Wood et al.,…”
• Plant immunity: towards an integrated view of plant–pathogen interactions (2010, background): “They interact specifically with a site in the target gene promoters through a central tandem repeat region that forms a DNA-binding domai”