Distinct functions of the two isoforms of dopamine D2 receptors

By A. Usiello, J. Baik, F. Rougé-Pont, R. Picetti, A. Dierich, M. Lemeur, P. Piazza, E. Borrelli. Nature, 2000

757 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/65b0ddf0522b25f8efb32915270cc4becaaf27bf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. J. Beaulieu
2. R. Gainetdinov

In Molecular Biology

1. J. Beaulieu
2. R. Gainetdinov

Citations in the corpus

• Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. (2003, background): “Both isoforms display distinct functions in vivo (24) as well as a differential ability to increase the steady state receptor concentration induced by dopamine in DRD2-transfected CHO-K1 cells (26).”
• The Physiology, Signaling, and Pharmacology of Dopamine Receptors (2011, background): “Therefore, the varying roles of the postsynaptic and presynaptic D2 dopamine receptors are probably determined by the different contributions of these isoforms (Usiello et al., 2000; De Mei et al., 2009).”
• Candidate gene studies of ADHD: a meta-analytic review (2009, neutral): “pathways (Usiello et al. 2000).”