The Physiology, Signaling, and Pharmacology of Dopamine Receptors

By J. Beaulieu, R. Gainetdinov. Pharmacological Reviews, 2011

2,689 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cd18d018978fceb726b5a92bf130d301af1e4d69

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In Cellular and Molecular Neuroscience

In Molecular Biology

Citations in the corpus

From Molecules to Management: Mechanisms and Consequences of Locust Phase Polyphenism (2017, background): “The second group, called D2-class dopamine receptors (D2, D3 and D4), mediate cAMP reduction by interaction with Gαi (Beaulieu and Gainetdinov, 2011; Callier et al., 2003; Cardinaud et al., 1998).”
Between Persistence and Flexibility: The Yin and Yang of Action Control (2015, background): “…how situational circumstances, experience, learning, and people’s cultural context can bias cognitive control states, and the information-processing characteristics they control, in predictable ways and even create chronic biases that outlive the conditions for which they were originally created.”
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. (2015, positive): “DA is not only an important neurotransmitter in the brain, but also functions as a local chemical messenger in several periphery parts of the body, including blood, intestine, and kidney (Beaulieu and Gainetdinov, 2011).”
Natural neural projection dynamics underlying social behavior. (2014, positive): “…are medium spiny neurons (MSNs), which can be divided into two broad categories defined by the type of DA receptor expressed (D1R or D2R, which couple to Gsand Gi- signaling pathways, respectively [Beaulieu and Gainetdinov, 2011], with different roles in modulating reward [Lobo and Nestler, 2011]).”
A genetically-encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice (2018, methodology): “To test the coupling of GRABDA sensors to GPCR downstream pathways, we examined the coupling efficacies of GRABDA sensors to either G protein- or b-arrestin-dependent pathways (Beaulieu and Gainetdinov, 2011).”
Beyond eye gaze: What else can eyetracking reveal about cognition and cognitive development? (2016, background): “The two main families of DA eceptors in the brain are D1-class receptors, abundant in prefrontal ortex, and D2-class receptors, primarily expressed in subcortical tructures like the striatum (Beaulieu and Gainetdinov, 2011).”
Dopaminergic modulation of synaptic transmission in cortex and striatum (2012, background): “The affinity of D2- like receptors for DA is generally reported to be 10-to 100-fold greater than that of D1-like receptors, with D3 and D4 receptors displaying the highest sensitivity for DA and D1 receptors the lowest (Beaulieu and Gainetdinov, 2011).”