Distribution of NF-κB-binding sites across human chromosome 22
By Rebecca Martone, G. Euskirchen, Paul Bertone, S. Hartman, Thomas E. Royce, Nicholas M. Luscombe, Johannes Rinn, F. Nelson, P. Miller, Mark Gerstein and 2 more. Proceedings of the National Academy of Sciences of the United States of America, 2003
310 citations recorded by the source corpus.
Subfields: Cancer Research, Immunology
View Paper: https://www.semanticscholar.org/paper/6556b35bfac2a168ac37f29bb6c065dac9fd2b41
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In Cancer Research
- Alexander Hoffmann
- Bing Lim
- X. Chen
- Thomas R. Gingeras
- Philipp Kapranov
- A. Willingham
- G. Natoli
- S. Ghosh
In Immunology
Citations in the corpus
- Genome-wide transcription and the implications for genomic organization (2007, result): “Comparable results were obtained for another transcription factor, NFκB ; approximately 28% of NFκB binding sites were found at the 5′ ends of genes and 22% were found more than 50 kb away from known gene”
- The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells (2006, background): “Previous work on mapping transcription factor binding sites using unbiased approaches shows that certain mammalian transcription factors can target sites outside proximal promoter element”
- Analysis of Transcription Factor HY5 Genomic Binding Sites Revealed Its Hierarchical Role in Light Regulation of Development[W] (2007, methodology): “…sites is located in the region proximal to the 59 ends (<5 to 10 kb upstream from the 59 ends), and the majority of binding sites were located in introns, near 39 ends, and even at unannotated regions (Weinmann et al., 2002; Martone et al., 2003; Cawley et al., 2004; Euskirchen et al., 2004).”
- Transcriptional regulation via the NF-κB signaling module (2006, background): “However, this degenerate kB DNA consensus sequence may still be more restrictive than what may be revealed by systematic in vitro (Linnell et al., 2004) and in vivo (Martone et al., 2003; Schreiber et al, 2006) studies.”