Regulation of enzymes of the urea cycle and arginine metabolism.

By S. Morris. Annual review of nutrition, 2002

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Regulation of immune responses by L-arginine metabolism (2005, background): “The 5′ flanking region of mouse ARG1 contains elements that control transcription in response to IL-4, cyclic AMP, TGF-β, dexamethasone and lipopolysaccharide (LPS”
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. (2005, background): “in the liver and kidneys, is also present in human red blood cells(22,23) and can be induced in many cell types by a variety of cytokines and inflammatory stimuli.(20,24,25) Furthermore, since arginineandornithinecompete for thesame transport system for cellular uptake,(26,27) a decrease in the rati”
Polyamines and cancer: old molecules, new understanding (2004, background): “All urea-cycle enzymes are expressed in the liver and, to a lesser degree, in the intestinal mucos”
Isolation of amniotic stem cell lines with potential for therapy (2007, background): “This represents a liver-specific function that requires the coordinated expression of several enzymes and specific mitochondrial amino acid transporter”