The machinery of macroautophagy

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Targeting autophagy in cancer (2018, background): “Conversely, the study of how selective autophagy targets specific organelles or proteins has engendered terms such as mitophagy, pexophagy, and xenophagy.(10) Recently, autophagy has been identified as a target for therapeutic intervention in several diseases, including cancer.”
Targeted protein degradation: mechanisms, strategies and application (2022, background): “During macroautophagy, dysfunctional proteins or organelles are recognized by autophagy receptors and selectively enclosed in autophagosomes.(76) Autophagosomes are then fuse with lysosomes and their contents are degraded.”
Autophagy and Tumor Metabolism (2017, background): “Indeed, this has been the subject of multiple excellent reviews (Feng et al., 2014; Klionsky and Codogno, 2013; Ktistakis and Tooze, 2016).”