A Proposed Classification of the Immunological Diseases
By D. McGonagle, M. McDermott. PLoS Medicine, 2006
798 citations recorded by the source corpus.
The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive immunity.
Subfields: Genetics, Molecular Biology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/635fad7046a65217bdbd7dda7b9527702e30cb76
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In Genetics
In Molecular Biology
- Daniel L. Kastner
- Gregory E. Miller
- A. Simon
- R. Mynatt
- I. Aksentijevich
- S. Masters
- E. Chen
- C. A. Dinarello
Citations in the corpus
- The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance (2011, background): “Therefore, obesity-associated inflammation may qualify as autoinflammation, which was defined by McGonagle and McDermott as self-directed tissue inflammation, where local factors at disease-prone sites determine activation of the innate immune syste”
- Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). (2009, background): “It should be stated at the outset that, as noted by McGonagle & McDermott (25), the spectrum of self-reactive immunological disease represents a continuum between autoimmune disorders based primarily on lesions of the adaptive immune system and autoinflammatory conditions rooted primarily in the inn”
- Psychological Stress in Childhood and Susceptibility to the Chronic Diseases of Aging: Moving Towards a Model of Behavioral and Biological Mechanisms (2011, background): “However, it is becoming increasingly clear that chronic inflammation driven by macrophages and neutrophils also contributes to maintaining disease activity (Choy & Panayi, 2001; McGonagle & McDermott, 2006).”
- The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease (2020, background): “Within these clear boundaries it is possible to stratify immune responses as being loss of function, normal or gain of function which then permits a better conceptual understanding of the integrated workings of the system [32] (Fig.”