Mobility of Plasmids

By Chris S. Smillie, M. P. Garcillán-Barcia, M. Francia, Eduardo P. C. Rocha, F. de la Cruz. Microbiology and Molecular Biology Reviews, 2010

1,075 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0a8a69970f52e0124584753648a09909fd82b291

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Citations in the corpus

Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies (2021, background): “Biofilm acts as a reservoir of antibiotic resistance genes (ARGs, the resistome) which are found to be responsible for providing antibiotic resistance to pathogens through HGT [109] conjugation [110, 111], transformation [112], and transduction [113, 114].”
PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures (2018, background): “In the context of plasmid sequences, the risk is even higher due to similar backbone elements, such as replication and conjugation transfer elements (8,67) and a large number of mobile genetic elements, such as insertion sequences and transposons (68), which are similarly structured.”
Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “It is facilitated by the conjugative machinery which is encoded either by genes on autonomously replicating plasmids or by integrative conjugative elements in the chromosome (Smillie et al., 2010; Wozniak and Waldor, 2010).”
Horizontal Gene Exchange in Environmental Microbiota (2011, background): “Bioinformatics of plasmid mobility suggests that globally about a quarter of all plasmids are potentially mobilizable and, therefore, can be transferred if a compatible conjugation machinery is present (Smillie et al., 2010).”
Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential (2015, methodology): “To detect potential conjugation systems on the plasmids, hidden Markov model (HMM) profiles of all well-described type 4 secretion systems [20, 21] were searched against the database of 4582 plasmid sequences using the hmmsearch program within HMMER (version 3.”
Acquired Antibiotic Resistance Genes: An Overview (2011, background): “Plasmids also commonly contain an origin of transfer and genes encoding functions that allow them to transfer to new hosts via conjugation (Smillie et al., 2010).”