Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
By Seong-Woon Yu, Shaida A. Andrabi, Hongmin Wang, N. Kim, G. Poirier, T. Dawson, Valina L. Dawson. Proceedings of the National Academy of Sciences of the United States of America, 2006
738 citations recorded by the source corpus.
Subfields: Electrical and Electronic Engineering, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/6280087b03284fc9d4e42e4764e2abf5abbeeb40
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Citations in the corpus
- NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences (2008, positive): “However, two recent studies suggested that PAR, instead ADP-ribose monomers, mediates PARP-1-induced AIF translocation and cell death (11, 333).”
- The expanding field of poly(ADP-ribosyl)ation reactions. ‘Protein Modifications: Beyond the Usual Suspects' Review Series (2008, background): “…where it induces large-scale DNa fragmentation and subsequent parp1 overactivation, leading to energy depletion and cell death (Moubarak et al, 2007; yu et al, 2006). parp1–/– mice and mice treated with parp inhibitors show protection from tissue injury and organ failure in various oxidative…”
- Mitochondria, oxidative metabolism and cell death in stroke. (2010, neutral): “The effects of PARP are explained, at least partially, by the ability of poly-ADP ribose to trigger release of AIF [127].”