Alginate derivatization: a review of chemistry, properties and applications.

By Siddhesh N. Pawar, K. Edgar. Biomaterials, 2012

1,464 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cell Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/60d1587baffcc3ed17220d840ec36cbf5c84e43f

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In Biomedical Engineering

1. R. Yahya
2. M. Oyen
3. H. Tan
4. C. Peteiro
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6. Jinchen Sun

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Citations in the corpus

• Thermal, microstructural, and spectroscopic analysis of Ca2+ alginate/clay nanocomposite hydrogel beads (2018, neutral): “Alginate is extracted from brown algae ( Phaeophyceae ) [5].”
• Effects of pH on the Shape of Alginate Particles and Its Release Behavior (2017, background): “With a pH value below the pKa of the uronic acid, alginate gels are stabilized by an intermolecular hydrogen bonding network [35].”
• Current progress on bio-based polymers and their future trends (2013, background): “Although alginates are a heterogeneous family of polymers with varying content of G and M blocks depending on the source of extraction, alginates with high G content have far more industrial importance (Siddhesh and Edgar 2012).”
• Alginate Production from Marine Macroalgae, with Emphasis on Kelp Farming (2018, background): “These commercial-grade alginates are now mainly used in biomedical applications and novel therapies [7, 36, 37], which have increased considerably in the last decade and are currently the most profitable, selling at the high end of the alginate market [43].”
• Alginate-Based Biomaterials for Regenerative Medicine Applications (2013, background): “Cell scaffolds play a crucial role because they act as an artificial ECM to provide a temporary environment to support the cell to infiltrate, adhere, proliferate and differentiate [1–3].”
• Applications of Alginate-Based Bioinks in 3D Bioprinting (2016, background): “Alginate is a naturally occurring, non-toxic, biodegradable and non-immunogenic linear polysaccharide composed of guluronic and mannuronic acids [11].”
• Macroalgal biorefinery concepts for the circular bioeconomy: A review on biotechnological developments and future perspectives (2021, background): “In the presence of divalent cations, the carbohydrate groups of G blocks in the alginate polysaccharide backbone are able to crosslink, thus constituting an egg-box model [169] which enables the formation and subsequent commercialisation of bio-degradable and edible bio-plastics.”
• pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications (2017, background): “The tetrabutylammonium salt of alginate is completely soluble in organic solvents like ethylene glycol as well as in water [92].”
• Super-elastic and highly hydrophobic/superoleophilic sodium alginate/cellulose aerogel for oil/water separation (2018, background): “SA and CN in the presence of divalent cations such as Ca2? can crosslink through ionic interactions between Ca2? and the carboxyl groups, which creates egg-box structures that improve swelling deformation resistance (Pawar and Edgar 2012) (Fig.”
• Current development of biodegradable polymeric materials for biomedical applications (2018, background): “The primary drawbacks of alginate are its generalized lack of strong mechanical properties, poor cell adhesion, and its lack of degradability in mammals.(128) However, by combining alginate with other biomaterials such as agarose and chitosan, and by partially oxidizing alginate with molecules like ”