Effects of pH on the Shape of Alginate Particles and Its Release Behavior

By J. Chuang, Yu-Ya Huang, Szu-Hsuan Lo, Tzu-Fang Hsu, Wen-Ying Huang, Shu-Ling Huang, Yung-Sheng Lin. 2017

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A vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As the first step, various shaped alginate particles were formed due to various pH values in gelation solutions. It was experimentally demonstrated that a low pH brought about an oblate shape, and particularly lower concentrations of both alginate and divalent cations resulted in a flattened oblate shape. Ba2

Subfields: Biomedical Engineering, Molecular Medicine, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/63eaae0073afe4589350946778ef5844e0c23d40