Mesendoderm Extension and Mantle Closure in Xenopus laevis Gastrulation: Combined Roles for Integrin α5β1, Fibronectin, and Tissue Geometry

By Lance A. Davidson, B. Hoffstrom, R. Keller, D. DeSimone. 2002

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Vertebrate Endoderm Development and Organ Formation (2009, background): “The anterior endoderm cells, on the other hand, exhibit directional migration, which requires Nodal signaling and is mediated by dynamic cell-cell adhesion and integrin-fibronectin interactions with the extra-cellular matrix (Davidson et al. 2002, Pezeron et al. 2008, Yamamoto et al. 2004).”
Intrinsic extracellular matrix properties regulate stem cell differentiation. (2010, background): “Moreover, interactions between specific germ layers and matrix proteins, e.g. mesendoderm morphogenesis and the synergy site of fibronectin (Davidson et al., 2002), also suggest a link between intrinsic matrix properties and differentiation.”
The Extracellular Matrix In Development and Morphogenesis: A Dynamic View (2009, background): “For example, the assembly of fibronectin fibrils along the blastocoel roof in amphibians precedes mesendoderm migration (Lee et al., 1984; Nakatsuji et al., 1985; Winklbauer, 1998), which in turn requires fibronectin adhesion (Boucaut et al., 1984; Davidson et al., 2002).”