Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor
By T. Ohtaki, Y. Shintani, S. Honda, H. Matsumoto, A. Hori, K. Kanehashi, Yasuko Terao, S. Kumano, Yoshihiro Takatsu, Y. Masuda and 11 more. Nature, 2001
1,420 citations recorded by the source corpus.
Subfields: Molecular Biology, Reproductive Medicine
View Paper: https://www.semanticscholar.org/paper/5e7e944303196d977899382e2e70aecb2a35d95a
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In Reproductive Medicine
Citations in the corpus
- Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity (2017, background): “, 2006) and the kisspeptin receptor GPR54 is expressed in GnRH neurons (Clements et al., 2001; Kotani et al., 2001; Muir et al., 2001; Ohtaki et al., 2001).”
- Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. (2004, background): “Metastin was initially purified from human placenta (11).”
- Ghrelin: structure and function. (2005, background): “In recent years, searches for novel ligands using orphan GPCR-expressing cells have resulted in the discovery of several novel bioactive peptides, such as nociceptin/orphanin FQ (157, 195), orexin/hypocretin (206), prolactin-releasing peptide (105), apelin (237), metastin (178), neuropeptide B (81, ”
- Kisspeptins and reproduction: physiological roles and regulatory mechanisms. (2012, background): “Although the mapping of the signaling pathways employed by GPR54 was initiated already in 2001 by the use of different heterologous cell systems (228, 292, 318), this aspect has received far less attention than the characterization of other facets of kisspeptin physiology and remains to date partial”