Inhibition of Retinoic Acid-Inducible Gene I-Mediated Induction of Beta Interferon by the NS1 Protein of Influenza A Virus

By M. Mibayashi, L. Martínez-Sobrido, Y. Loo, Washington B Cárdenas, M. Gale, A. García‐Sastre. Journal of Virology, 2006

626 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/5e465a5622e594871095dff032a36c7ab215f512

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Shizuo Akira
2. T. Mogensen
3. R. Randall
4. S. Goodbourn
5. Y. Loo
6. M. Gale
7. A. García‐Sastre
8. A. Bowie

In Oncology

1. Shizuo Akira
2. T. Mogensen
3. M. Gale
4. Y. Loo
5. J. Rehwinkel
6. Michael G. Katze
7. R. Randall
8. S. Goodbourn

Citations in the corpus

• Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by RIG-I (2009, background): “Woo, and Luis Martı́nez-Sobrido for kindly providing the monoclonal NS1 antibody (Mibayashi et al., 2007) VSV-GFP (Ebert et al.”
• Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity (2007, result): “This supports previous findings that the influenza virus A/PR/8/34 NS1 protein can attenuate RIG-I signaling of IRF-3 activation (11, 28, 29, 31).”
• RIG-I detects viral genomic RNA during negative-strand RNA virus infection. (2010, background): “NS1 can interact with RIG-I (Mibayashi et al., 2007), especially in the presence of stimulatory RNA through formation of a trimeric complex (Figures S4A–S4D) (Pichlmair et al., 2006).”
• The multifunctional NS1 protein of influenza A viruses. (2008, background): “As such, recent work now indicates that PR8/NS1 may mediate its pre-transcriptional block on IFN-b induction by forming a complex with RIG-I (Guo et al., 2007; Mibayashi et al., 2007; Opitz et al., 2007; Pichlmair et al., 2006).”
• Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. (2008, background): “…either directly or indirectly, with RIG-I (but not mda-5) to inhibit its activity 20 Journal of General Virology 89 Downloaded from www.microbiologyresearch.org by IP: 54.70.40.11 On: Thu, 06 Dec 2018 10:52:31 (Guo et al., 2006; Opitz et al., 2006; Pichlmair et al., 2006; Mibayashi et al., 2007).”
• Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses (2009, background): “action with RIG-I/IPS-1 (49, 250, 295), the result being inhi-”
• Viral evasion and subversion of pattern-recognition receptor signalling (2008, background): “Influenza A virus NS1 protein binds to the RIG-I–IPS1 complex and blocks downstream signallin”