Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation

By P. Shaw, Kristen L. Eckstrand, W. Sharp, J. Blumenthal, Jason P. Lerch, Dede K. Greenstein, Liv S. Clasen, Alan C. Evans, Jay N. Giedd, Judith L. Rapoport. Proceedings of the National Academy of Sciences of the United States of America, 2007

1,752 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/5d386c85f0334da7639acc04915b9fc4743f79f4

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Citations in the corpus

Adult ADHD and comorbid disorders: clinical implications of a dimensional approach (2017, methodology): “Neuroanatomical gradations in “cool” processing appear to be related to prefrontal dysfunction involving the dorsolateral prefrontal cortex (dlPFC), and the parietal cortex, insula cortex and anterior cingulate cortex (ACC) are also critically involved in executive function as part of a frontal-pari”
The diagnosis of mental disorders: the problem of reification. (2010, background): “In ADHD, a recent longitudinal structural neuroimaging study that examined changes in cortical thickness with age concluded that symptoms result from maturational delay, especially of prefrontal cortex, but not from a qualitatively abnormal pattern of cortical development (Shaw et al. 2007).”
Development of Large-Scale Functional Brain Networks in Children (2009, background): “that are thought to be characterized by disruptions in synaptic pruning and myelination at the neuronal level [92–94].”
Performing Label-Fusion-Based Segmentation Using Multiple Automatically Generated Templates (2012, background): “Half of the subjects suffer from attention deﬁcit hyperactivity disorder (ADHD) while the other half are healthy normal controls [Shaw et al., 2007, 2011].”
Neuroethics, Neuroeducation, and Classroom Teaching: Where the Brain Sciences Meet Pedagogy (2012, background): “, [10]), as well as how symptoms of attention-deficit/hyperactivity disorder (ADHD) may represent developmental delay rather than damage in the brain [11].”
Children's Brain Development Benefits from Longer Gestation (2011, background): “…Orange, CA, USA 6 Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, CA, USA Disruptions to brain development associated with shortened gestation place individuals at risk for the development of behavioral and psychological dysfunction throughout the lifespan.”
Development of the Cerebral Cortex across Adolescence: A Multisample Study of Inter-Related Longitudinal Changes in Cortical Volume, Surface Area, and Thickness (2017, background): “…to cortical thickness, with some indicating inverted-U trajectories from childhood to adulthood, with estimates of peak thickness in late childhood (Shaw et al., 2007, 2008; Raznahan et al., 2011), while others show widespread monotonic decreases during childhood and adolescence (Sowell et al.,…”
Trajectories of cortical thickness maturation in normal brain development – The importance of quality control procedures (2015, positive): “The rate of cortical thinningwas found to be associated with the development of neuropsychiatric disorders (Thormodsen et al., 2013; Shaw et al., 2007) and could constitute a potential biomarker for disease states.”
Verbal Memory Interference in Attention-Deficit Hyperactivity Disorder: A Meta-Analytic Review (2022, background): “The lower susceptibility to PI observed in children may be linked to the incomplete development of executive functions and the maturity of the prefrontal cortex among children, as extant literature documents a 3-year delay in cortical maturation relative to typically developing peers (Shaw et al., 2”
Adverse childhood experiences, allostasis, allostatic load, and age-related disease. (2012, background): “frontal cortex, similar to findings in children with attention deficit and hyperactivity disorder [71,72], or to neuronal damage.”
Structural MRI of Pediatric Brain Development: What Have We Learned and Where Are We Going? (2010, positive): “Such studies indicate a developmental delay of cortical thickness trajectories most markedly for the frontal lobes (Shaw et al., 2007a) (see Figure 3).”
Relating ADHD to the aperiodic component of the EEG signal in both males and females across development (2026, unknown): “Importantly, ADHD has been linked to an approximately 3-year delay in attaining peak cortical thickness as well as a slower rate of cortical thinning throughout late childhood and adolescence (8 – 18 years) throughout most of the prefrontal and lateral temporal cortices (Shaw et al., 2007; 2013).”