Mobilized bone marrow cells repair the infarcted heart, improving function and survival

By D. Orlic, J. Kajstura, S. Chimenti, Federica Limana, Igor Jakoniuk, F. Quaini, B. Nadal-Ginard, D. Bodine, A. Leri, P. Anversa. Proceedings of the National Academy of Sciences of the United States of America, 2001

2,251 citations recorded by the source corpus.

Subfields: Biomaterials, Cardiology and Cardiovascular Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/5cabcd64f0e7cb1ab8f403d563b918fd7a9fb31c

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Citations in the corpus

Unchain my heart: the scientific foundations of cardiac repair. (2005, methodology): “and SCF (Kit ligand) — were used to improve cardiac regeneration experimentally (60), which quickly led to the initiation of clinical trials studying the ability of G-CSF to mobilize stem/progenitor”
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis (2002, background): “Contrary to the conventional assumption that damaged tissues are repaired by individual parenchymal cells, an accumulating body of evidence indicates that there are somatic stem cells that are mobilized to remote organs, where they differentiate into required lineages and participate in organ repair”
Plasticity of marrow-derived stem cells. (2003, positive): “A related study demonstrates that stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF), which increase the circulating pool of BMSC forty-fold, can lead to improved cardiac outcome post-infarct when administered during the peri-infarct period.(39) While it may be that these growt”