In vivo magnetic resonance imaging of transgene expression

By Ralph Weissleder, A. Moore, Umar Mahmood, R. Bhorade, Helene Benveniste, E. Chiocca, J. Basilion. Nature Medicine, 2000

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Applications of magnetic nanoparticles in biomedicine (2003, positive): “This process leads to the production of increased numbers of certain cell wall receptors, which in turn can be targeted using specially coated nanoparticles, thereby allowing a differentiation between the expressing cells and their surroundings [137].”
Molecular imaging in living subjects: seeing fundamental biological processes in a new light. (2003, background): “Weissleder et al. (2000) and Moore et al. (2001) have also assessed the transferrin receptor as anMRI reporter in rat gliosarcoma 9L cell xenografts (Fig.”
Magnetic relaxation switches capable of sensing molecular interactions (2002, background): “Highly uniform magnetic nanoparticles can be prepared with defined surface characteristics that allow covalent and stoichiometric attachment of oligonucleotides, nucleic acids, small molecules, peptides, receptor ligands, proteins, and antibodie”
Scaling down imaging: molecular mapping of cancer in mice (2002, background): “and tumour-specific markers such as receptors and transgene product”