The role of microglia in amyloid clearance from the AD brain
By C. D. Lee, G. Landreth. Journal of neural transmission, 2010
672 citations recorded by the source corpus.
Subfields: Clinical Biochemistry, Neurology, Physiology
View Paper: https://www.semanticscholar.org/paper/5c86d452c04b896fdf6dabd3e50a5e9a0d423c5a
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In Clinical Biochemistry
In Neurology
In Physiology
Citations in the corpus
- The myeloid cells of the central nervous system parenchyma (2010, background): “Complexity is inherent in the biology: signalling downstream of the recognition of fibrillar amyloid-β peptides by microglia involves an aggregate comprising various combinations of nine transmembrane and endosomal proteins, including class A and B scavenger receptors, α 6 β 1 -integrin, CD14, CD47,”
- Microglial cell origin and phenotypes in health and disease (2011, background): “Many reports have suggested that microglial cell-mediated phagocytosis of amyloid-β is essential for the clearance of plaque”
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed (2014, background): “microglia [123], astrocytes [124], and possibly neurons [125].”