Model morphing and sequence assignment after molecular replacement

By T. C. Terwilliger, Randy J. Read, Paul D. Adams, A. Brunger, Pavel V. Afonine, Li-Wei Hung. 2013

36 citations recorded by the source corpus.

A procedure for model building is described that combines morphing a model to match a density map, trimming the morphed model and aligning the model to a sequence.

Subfields: Materials Chemistry, Physical and Theoretical Chemistry

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. Paul D. Adams
2. Pavel V. Afonine
3. Randy J. Read
4. T. C. Terwilliger
5. Nigel W. Moriarty
6. T. Croll
7. A. McCoy
8. Jane S. Richardson

In Physical and Theoretical Chemistry

1. Randy J. Read
2. M. Sammito
3. T. Croll
4. Pavel V. Afonine
5. Alexandre Urzhumtsev
6. A. McCoy
7. Paul D. Adams
8. T. C. Terwilliger

Citations in the corpus

• Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix (2019, methodology): “The default mode performs gradient-driven minimization of the entire model, but optimization can also be performed using simulated annealing, morphing (Terwilliger et al., 2013), rigidbody refinement and systematic side-chain improvement (Oldfield, 2001).”
• Current approaches for the fitting and refinement of atomic models into cryo-EM maps using CCP-EM (2018, methodology): “Specifically, Jiggle Fit helps to appropriately position and orient the atomic model (rigidbody fitting), and Model Morphing (Terwilliger et al., 2013) allows localized regions to be fitted into the map by applying Figure 6 The Divide and Conquer procedure illustrated using a model of a rotavirus…”