Monocytes and macrophages: developmental pathways and tissue homeostasis

By Florent Ginhoux, Steffen Jung. Nature reviews. Immunology, 2014

1,763 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/5c15243c0334d0be206c1fe1a16c18229320636b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. M. Guilliams
2. A. Mildner
3. Steffen Jung
4. Florent Ginhoux
5. P. Italiani
6. D. Boraschi
7. C. Varol
8. S. Yona

Citations in the corpus

• Tissue-Resident Macrophage Ontogeny and Homeostasis. (2016, background): “…and by the loss of CD135 expression in the case of cMOPs (Hettinger et al., 2013). cMOPs give rise to bothmonocyte subsets, the Ly6Chi and Ly6Clo populations, whose Immunity 44, March 15, 2016 ª2016 Elsevier Inc. 439 relationship is still controversial (recently reviewed in Ginhoux and Jung, 2014).”
• Macrophage plasticity, polarization, and function in health and disease (2018, background): “During resolution, M2 macrophages are a major source of lipid mediators and produce anti-inflammatory cytokines, IL-10 and TGF-β involved in tissue resolution (Das et al., 2015; Ginhoux & Jung, 2014; Hinz et al., 2012; Mantovani et al., 2013).”
• Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species (2019, background): “In humans, these are identified in blood as CD14+ (so called ‘classical’) and CD14int CD16+ (‘nonclassical’) (Ginhoux and Jung, 2014).”
• The fate and lifespan of human monocyte subsets in steady state and systemic inflammation (2017, background): “Collectively, the cells of the mononuclear phagocyte system play key functions in maintaining tissue homeostasis during steady state as well as orchestrating the genesis and resolution of the immune response (Davies et al., 2013; Wynn et al., 2013; Ginhoux and Jung, 2014).”
• Progress in tumor-associated macrophage (TAM)-targeted therapeutics (2017, neutral): “Macrophage functions are as diverse as their lineages and play important roles in normal homeostasis and disease development [4][5].”