Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates.

By S. Devine, C. Cobbs, Matt Jennings, A. Bartholomew, R. Hoffman. Blood, 2003

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View Paper: https://www.semanticscholar.org/paper/5ba3d1d750b43a865f9515caffe3f6906de178dc

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In Genetics

O. Ringdén

Citations in the corpus

Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion (2012, methodology): “ORIGINAL RESEARCH ARTICLE published: 26 September 2012 doi: 10.3389/fimmu.2012.00297 Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion”
Immunomodulatory effect of human adipose tissue‐derived adult stem cells: comparison with bone marrow mesenchymal stem cells (2005, background): “It was previously shown in a baboon model that infused MSCs only poorly migrate in spleen and lymph nodes, where immune responses are initiated and where MSCs could inhibit lymphocyte activation (Devine et al, 2003).”
Mesenchymal stem cell homing: the devil is in the details. (2009, neutral): “, 2008), and (2) nonspecifically distribute throughout various tissues and organs (Devine et al., 2003) including the lung, liver, kidney, and spleen, where a high percentage of infused cells are often observed (Barbash et al.”
The In Vitro Migration Capacity of Human Bone Marrow Mesenchymal Stem Cells: Comparison of Chemokine and Growth Factor Chemotactic Activities (2007, background): “As reported in murine [18], simian [19-21] or human [22] models, following systemic infusion into the bloodstream, BM MSCs are able to colonize and long-term persist in a wide range of tissues, that include, in addition to BM, muscle, skin, gut, at IH M ed L ib on Jne 4, 2007 w w w .”
Mesenchymal stem cells in health and disease (2008, background): “Transplantation experiments in non-human primates have shown that MSCs can spread to many tissues after intravenous administratio”
HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. (2003, background): “Discussion Mesenchymal stem cells distribute to a wide variety of tissues following systemic or intraperitoneal injection [6,20].”