The Common γ Chain (γc) Is a Required Signaling Component of the IL-21 Receptor and Supports IL-21-Induced Cell Proliferation via JAK3†
By T. Habib, S. Senadheera, K. Weinberg, K. Kaushansky. 2002
215 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/5a48aa410b4c1a8ae65599a6af58c0374b9b761e
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In Immunology
Citations in the corpus
- The biological functions of T helper 17 cell effector cytokines in inflammation. (2008, unknown): “Correspondingly , the functional IL-21 receptor for IL-21 consists of IL-21R and g c (Asao et al., 2001; Habib et al., 2002).”
- IL-21 Induces Differentiation of Human Naive and Memory B Cells into Antibody-Secreting Plasma Cells1 (2005, background): “It is of considerable interest that IL-4R ligation induces primarily STAT6, which is essential for IL-4 signaling, including IL-4-induced up-regulation of AID in both mice and humans (39, 40), whereas IL-21R engagement activates primarily STAT1 and -3 and more weakly STAT5 (1, 53 , 54).”