σB Modulates Virulence Determinant Expression and Stress Resistance: Characterization of a Functional rsbU Strain Derived from Staphylococcus aureus 8325-4

By M. Horsburgh, J. Aish, Ian J. White, L. Shaw, J. Lithgow, S. Foster. Journal of Bacteriology, 2002

729 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. (2010, methodology): “aureus (23), and it has been previously used to study S.”
Identification of Genes Involved in Polysaccharide-Independent Staphylococcus aureus Biofilm Formation (2010, neutral): “SH1000 sigB derivative of NCTC8325-4 [56]”
Microarray-Based Analysis of the Staphylococcus aureus σB Regulon (2004, background): “(44, 84), proteases (34, 36, 84), and thermonuclease (44, 84).”
Autoinduction and signal transduction in the regulation of staphylococcal virulence (2003, background): “Derivatives of 8325 strains in which rsbU has been repaired (Bischoff et al., 2001; Horsburgh et al., 2002) show important differences in the overall biology of the organism, including a reduction in the lag phase of growth, an increase in overall growth yield and in starvation survival (Horsburgh…”
Intracellular staphylococcus aureus: Live-in and let die (2012, positive): “Further, SCVs display a thick cell wall (Bulger and Bulger, 1967) and an up-regulation of alternative sigma-factor σB (Moisan et al., 2006), which enables S. aureus to cope with a variety of environmental stressors (Horsburgh et al., 2002).”