Mechanism and medical implications of mammalian autophagy
By Ivan Dikic, Zvulun Elazar. Nature reviews. Molecular cell biology, 2018
2,500 citations recorded by the source corpus.
Subfields: Epidemiology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/3adfd6456de359fca81b24bd84c497cba6b605e5
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Citations in the corpus
- Autophagy-Independent Functions of the Autophagy Machinery (2019, background): “The molecular apparatus that underlies these multiple variants of autophagy has been characterized with increasing precision (Dikic and Elazar, 2018) (Box 1).”
- TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019 (2019, background): “Autophagy describes a cellular survival program during which lysosomes degrade substrates intracellularly for energy production and depletion of damaged cellular components [243].”
- Lysosomes as a therapeutic target (2019, background): “In addition, sub stantial efforts have been focused on therapeutically targeting the autophagy processes upstream of lyso somes [11] [12] [13] [14] .”
- A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress (2020, background): “Autophagy is an intracellular degradation process where eukaryotic cells remove harmful or unwanted cytoplasmic contents to maintain cellular homeostasis (Dikic and Elazar, 2018; Klionsky et al., 2011; Marshall and Vierstra, 2018).”
- Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy (2022, background): “OVERVIEW OF AUTOPHAGY Eukaryotic cells utilize autophagy for maintaining homeostasis and managing lipid metabolism.(44,45) Activated by various stress states, autophagic membrane structures are formed to engulf and degrade intracellular structures, including damaged organelles, unfolded proteins, an”
- Autophagy-Dependent Ferroptosis: Machinery and Regulation (2020, background): “Autophagy is a dynamic process that relies on the formation and maturation of specific membrane structures such as phagophores, autophagosomes, and autolysosomes (Dikic and Elazar, 2018) (Fig.”