Natural Polyphenols for Prevention and Treatment of Cancer

By Yue Zhou, Jie Zheng, Ya Li, Dong-ping Xu, Sha Li, Yu-ming Chen, Huabin Li. Nutrients, 2016

663 citations recorded by the source corpus.

There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatment of cancer. Potential mechanisms included antioxidant, anti-inflammation as well as the modulation of multiple molecular events involved in carcinogenesis. The current review summarized the anticancer efficacy of major polyphenol classes (flavonoids, phenolic acids, lignans and stilbenes) and discussed the potential mechanisms of action, which were based on epidemiological, in vitro, in vivo and clinical studies within the past five years.

Subfields: Biochemistry, Pathology and Forensic Medicine, Pharmacology

View Paper: https://www.semanticscholar.org/paper/57ab87e5996f868d3f19bb8a95ea14ec7452bde1

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Citations in the corpus

• The Role of Polyphenols in Human Health and Food Systems: A Mini-Review (2018, background): “pressure, to increase overall vascular health (15, 23).”
• Polyphenols: A concise overview on the chemistry, occurrence, and human health (2019, result): “Despite encouraging experimental data, clinical results have not provided univocal results and should be also mentioned that some polyphenols, such as genistein and daidzein, might adversely affect hormone‐related cancer (Zhou et al., 2016).”