Proteolytic processing and cell biological functions of the amyloid precursor protein.

By B. de Strooper, W. Annaert. Journal of Cell Science, 2000

658 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

An Overview of APP Processing Enzymes and Products (2010, unknown): “…has a constitutive and an inducible component that depends on its subcellular localization. α-secretase at the plasma membrane surface is considered constitutively active and it is believed to be the main proteolytic pathway for APP that reaches the plasma membrane (de Strooper and Annaert, 2000).”
Autophagy, amyloidogenesis and Alzheimer disease (2007, unknown): “Recent reviews of other aspects of A and APP biology are available (Zheng and Koo, 2006; De Strooper and Annaert, 2000), and these are covered here only briefly for background information.”
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts (2003, background): “Th e Jo ur na l o f C el l B io lo gy The Rockefeller University Press, 0021-9525/2003/01/113/11 $8.00 The Journal of Cell Biology, Volume 160, Number 1, January 6, 2003 113–123 http://www.jcb.org/cgi/doi/10.1083/jcb.200207113 JCB Article 113”