Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120.

By T. Kaneko, Yasukazu Nakamura, C. Wolk, T. Kuritz, S. Sasamoto, A. Watanabe, Mayumi Iriguchi, Atsuko Ishikawa, K. Kawashima, Takaharu Kimura and 12 more. DNA Research, 2001

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The nucleotide sequence of the entire genome of a filamentous cyanobacterium, Anabaena sp. strain PCC 7120, was determined. The genome of Anabaena consisted of a single chromosome (6,413,771 bp) and six plasmids, designated pCC7120alpha (408,101 bp), pCC7120beta (186,614 bp), pCC7120gamma (101,965 bp), pCC7120delta (55,414 bp), pCC7120epsilon (40,340 bp), and pCC7120zeta (5,584 bp). The chromosome bears 5368 potential protein-encoding genes, four sets of rRNA genes, 48 tRNA genes representing 42 tRNA species, and 4 genes for small structural RNAs. The predicted products of 45% of the potential protein-encoding genes showed sequence similarity to known and predicted proteins of known function, and 27% to translated products of hypothetical genes. The remaining 28% lacked significant similarity to genes for known and predicted proteins in the public DNA databases. More than 60 genes involved in various processes of heterocyst formation and nitrogen fixation were assigned to the chromosome based on their similarity to the reported genes. One hundred and ninety-five genes coding for components of two-component signal transduction systems, nearly 2.5 times as many as those in Synechocystis sp. PCC 6803, were identified on the chromosome. Only 37% of the Anabaena genes showed significant sequence similarity to those of Synechocystis, indicating a high degree of divergence of the gene information between the two cyanobacterial strains.

Subfields: Ecology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/55e9ab53e5f305d0dd3926edfc519e744a04aa61

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Citations in the corpus

• Role of Lipids and Fatty Acids in Stress Tolerance in Cyanobacteria (2002, background): “…unicellular cyanobacterium, Synechocystis p. strain PCC 6803 (3.57 Mb plus sequenced plasmids) and the filamentous, heterocyst-forming cyanobacterium, Anabaena spp. strain PCC 7120 (6.41 Mb plus sequenced plasmids) (Kaneko and Tabata 1997, Kaneko et al. 2001a; see http://www.kazusa.or.jp/cyano/).”
• Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing (2012, background): “Some of these proteins, such as CBPIV, have previously been annotated as PsbC homologs (25), because all CBP proteins are thought to have a common evolutionary origin with the psbC gene (24).”